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Speech Sound Processing Deficits and Training-Induced Neural Plasticity in Rats with Dyslexia Gene Knockdown
In utero RNAi of the dyslexia-associated gene Kiaa0319 in rats (KIA-) degrades cortical responses to speech sounds and increases trial-by-trial variability in onset latency. We tested the hypothesis that KIA- rats would be impaired at speech sound discrimination. KIA- rats needed twice as much train...
Autores principales: | Centanni, Tracy M., Chen, Fuyi, Booker, Anne M., Engineer, Crystal T., Sloan, Andrew M., Rennaker, Robert L., LoTurco, Joseph J., Kilgard, Michael P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4037188/ https://www.ncbi.nlm.nih.gov/pubmed/24871331 http://dx.doi.org/10.1371/journal.pone.0098439 |
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