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Differences in PGE(2) Production between Primary Human Monocytes and Differentiated Macrophages: Role of IL-1β and TRIF/IRF3
Prostaglandin E2 (PGE(2)) is induced in vivo by bacterial products including TLR agonists. To determine whether PGE(2) is induced directly or via IL-1β, human monocytes and macrophages were cultured with LPS or with Pam3CSK4 in presence of caspase-1 inhibitor, ZVAD, or IL-1R antagonist, Kineret. TLR...
Autores principales: | Endo, Yukinori, Blinova, Ksenia, Romantseva, Tatiana, Golding, Hana, Zaitseva, Marina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4037220/ https://www.ncbi.nlm.nih.gov/pubmed/24870145 http://dx.doi.org/10.1371/journal.pone.0098517 |
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