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Genetic aspects of athletic performance: the African runners phenomenon
The current dominance of African runners in long-distance running is an intriguing phenomenon that highlights the close relationship between genetics and physical performance. Many factors in the interesting interaction between genotype and phenotype (eg, high cardiorespiratory fitness, higher hemog...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4037248/ https://www.ncbi.nlm.nih.gov/pubmed/24891818 http://dx.doi.org/10.2147/OAJSM.S61361 |
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author | Vancini, Rodrigo Luiz Pesquero, João Bosco Fachina, Rafael Júlio Andrade, Marília dos Santos Borin, João Paulo Montagner, Paulo César de Lira, Claudio Andre Barbosa |
author_facet | Vancini, Rodrigo Luiz Pesquero, João Bosco Fachina, Rafael Júlio Andrade, Marília dos Santos Borin, João Paulo Montagner, Paulo César de Lira, Claudio Andre Barbosa |
author_sort | Vancini, Rodrigo Luiz |
collection | PubMed |
description | The current dominance of African runners in long-distance running is an intriguing phenomenon that highlights the close relationship between genetics and physical performance. Many factors in the interesting interaction between genotype and phenotype (eg, high cardiorespiratory fitness, higher hemoglobin concentration, good metabolic efficiency, muscle fiber composition, enzyme profile, diet, altitude training, and psychological aspects) have been proposed in the attempt to explain the extraordinary success of these runners. Increasing evidence shows that genetics may be a determining factor in physical and athletic performance. But, could this also be true for African long-distance runners? Based on this question, this brief review proposed the role of genetic factors (mitochondrial deoxyribonucleic acid, the Y chromosome, and the angiotensin-converting enzyme and the alpha-actinin-3 genes) in the amazing athletic performance observed in African runners, especially the Kenyans and Ethiopians, despite their environmental constraints. |
format | Online Article Text |
id | pubmed-4037248 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Dove Medical Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-40372482014-06-02 Genetic aspects of athletic performance: the African runners phenomenon Vancini, Rodrigo Luiz Pesquero, João Bosco Fachina, Rafael Júlio Andrade, Marília dos Santos Borin, João Paulo Montagner, Paulo César de Lira, Claudio Andre Barbosa Open Access J Sports Med Review The current dominance of African runners in long-distance running is an intriguing phenomenon that highlights the close relationship between genetics and physical performance. Many factors in the interesting interaction between genotype and phenotype (eg, high cardiorespiratory fitness, higher hemoglobin concentration, good metabolic efficiency, muscle fiber composition, enzyme profile, diet, altitude training, and psychological aspects) have been proposed in the attempt to explain the extraordinary success of these runners. Increasing evidence shows that genetics may be a determining factor in physical and athletic performance. But, could this also be true for African long-distance runners? Based on this question, this brief review proposed the role of genetic factors (mitochondrial deoxyribonucleic acid, the Y chromosome, and the angiotensin-converting enzyme and the alpha-actinin-3 genes) in the amazing athletic performance observed in African runners, especially the Kenyans and Ethiopians, despite their environmental constraints. Dove Medical Press 2014-05-20 /pmc/articles/PMC4037248/ /pubmed/24891818 http://dx.doi.org/10.2147/OAJSM.S61361 Text en © 2014 Vancini et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. |
spellingShingle | Review Vancini, Rodrigo Luiz Pesquero, João Bosco Fachina, Rafael Júlio Andrade, Marília dos Santos Borin, João Paulo Montagner, Paulo César de Lira, Claudio Andre Barbosa Genetic aspects of athletic performance: the African runners phenomenon |
title | Genetic aspects of athletic performance: the African runners phenomenon |
title_full | Genetic aspects of athletic performance: the African runners phenomenon |
title_fullStr | Genetic aspects of athletic performance: the African runners phenomenon |
title_full_unstemmed | Genetic aspects of athletic performance: the African runners phenomenon |
title_short | Genetic aspects of athletic performance: the African runners phenomenon |
title_sort | genetic aspects of athletic performance: the african runners phenomenon |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4037248/ https://www.ncbi.nlm.nih.gov/pubmed/24891818 http://dx.doi.org/10.2147/OAJSM.S61361 |
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