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Properdin has an ascendancy over factor H regulation in complement-mediated renal tubular damage

BACKGROUND: Urinary (U)-complement components have been detected in patients with proteinuric renal diseases, and complement activation via the alternative pathway (AP) is believed to play a role in renal tubular damage. The present study aimed to examine the regulation of complement AP activation i...

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Detalles Bibliográficos
Autores principales: Nagamachi, Seiji, Ohsawa, Isao, Suzuki, Hiyori, Sato, Nobuyuki, Inoshita, Hiroyuki, Hisada, Atsuko, Honda, Daisuke, Shimamoto, Mamiko, Shimizu, Yoshio, Horikoshi, Satoshi, Tomino, Yasuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4037424/
https://www.ncbi.nlm.nih.gov/pubmed/24885016
http://dx.doi.org/10.1186/1471-2369-15-82