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Quantitative measurements of HER2 and phospho-HER2 expression: correlation with pathologic response to neoadjuvant chemotherapy and trastuzumab

BACKGROUND: Preoperative therapy with chemotherapy and the HER2-targeted monoclonal antibody trastuzumab is valuable for patients with large or locally advanced HER2-positive (HER2+) breast cancers but traditional methods of measuring HER2 expression do not accurately stratify patients for likelihoo...

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Detalles Bibliográficos
Autores principales:	Cheng, Huan, Bai, Yalai, Sikov, William, Sinclair, Natalie, Bossuyt, Veerle, Abu-Khalaf, Maysa M, Harris, Lyndsay N, Rimm, David L
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4037428/ https://www.ncbi.nlm.nih.gov/pubmed/24885187 http://dx.doi.org/10.1186/1471-2407-14-326

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