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The spatial organization of non-homologous end joining: From bridging to end joining

Non-homologous end joining (NHEJ) repairs DNA double-strand breaks generated by DNA damage and also those occurring in V(D)J recombination in immunoglobulin and T cell receptor production in the immune system. In NHEJ DNA-PKcs assembles with Ku heterodimer on the DNA ends at double-strand breaks, in...

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Detalles Bibliográficos
Autores principales: Ochi, Takashi, Wu, Qian, Blundell, Tom L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4037875/
https://www.ncbi.nlm.nih.gov/pubmed/24636752
http://dx.doi.org/10.1016/j.dnarep.2014.02.010

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