Cargando…
The spatial organization of non-homologous end joining: From bridging to end joining
Non-homologous end joining (NHEJ) repairs DNA double-strand breaks generated by DNA damage and also those occurring in V(D)J recombination in immunoglobulin and T cell receptor production in the immune system. In NHEJ DNA-PKcs assembles with Ku heterodimer on the DNA ends at double-strand breaks, in...
Autores principales: | Ochi, Takashi, Wu, Qian, Blundell, Tom L. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4037875/ https://www.ncbi.nlm.nih.gov/pubmed/24636752 http://dx.doi.org/10.1016/j.dnarep.2014.02.010 |
Ejemplares similares
-
Structural Biology of DNA Repair: Spatial Organisation of the Multicomponent Complexes of Nonhomologous End Joining
por: Ochi, Takashi, et al.
Publicado: (2010) -
A Single XLF Dimer Bridges DNA Ends During Non-Homologous End Joining
por: Graham, Thomas G.W., et al.
Publicado: (2018) -
Stages, scaffolds and strings in the spatial organisation of non-homologous end joining: Insights from X-ray diffraction and Cryo-EM
por: Liang, Shikang, et al.
Publicado: (2021) -
Non-homologous end joining in class switch recombination: the beginning of the end
por: Kotnis, Ashwin, et al.
Publicado: (2008) -
Non-homologous end joining repair in Xenopus egg extract
por: Zhu, Songli, et al.
Publicado: (2016)