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Atomistic Autophagy: The Structures of Cellular Self-Digestion

Autophagy is directed by numerous distinct autophagy-related (Atg) proteins. These transmit starvation-induced signals to lipids and regulatory proteins and assemble a double-membrane autophagosome sequestering bulk cytoplasm and/or selected cargos destined for degradation upon autophagosome fusion...

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Detalles Bibliográficos
Autores principales: Hurley, James H., Schulman, Brenda A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038036/
https://www.ncbi.nlm.nih.gov/pubmed/24725401
http://dx.doi.org/10.1016/j.cell.2014.01.070