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Steady-state Carbamazepine Pharmacokinetics following Oral and Stable-Labeled Intravenous Administration in Epilepsy Patients: Effect of Race and Sex

Carbamazepine is a widely prescribed antiepileptic drug. Due to a lack of an intravenous formulation, its absolute bioavailability, absolute clearance, and half-life in patients at steady state have not been determined. We developed an intravenous, stable-labeled (SL) formulation in order to charact...

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Detalles Bibliográficos
Autores principales: Marino, SE, Birnbaum, AK, Leppik, IE, Conway, JM, Musib, LC, Brundage, RC, Ramsay, RE, Pennell, PB, White, JR, Gross, CR, Rarick, JO, Mishra, U, Cloyd, JC
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038037/
https://www.ncbi.nlm.nih.gov/pubmed/22278332
http://dx.doi.org/10.1038/clpt.2011.251