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Steady-state Carbamazepine Pharmacokinetics following Oral and Stable-Labeled Intravenous Administration in Epilepsy Patients: Effect of Race and Sex
Carbamazepine is a widely prescribed antiepileptic drug. Due to a lack of an intravenous formulation, its absolute bioavailability, absolute clearance, and half-life in patients at steady state have not been determined. We developed an intravenous, stable-labeled (SL) formulation in order to charact...
Autores principales: | Marino, SE, Birnbaum, AK, Leppik, IE, Conway, JM, Musib, LC, Brundage, RC, Ramsay, RE, Pennell, PB, White, JR, Gross, CR, Rarick, JO, Mishra, U, Cloyd, JC |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038037/ https://www.ncbi.nlm.nih.gov/pubmed/22278332 http://dx.doi.org/10.1038/clpt.2011.251 |
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