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Inhibition of soluble epoxide hydrolase is renoprotective in 5/6 nephrectomized Ren-2 transgenic hypertensive rats
1. The aim of the present study was to test the hypothesis that increasing kidney tissue concentrations of epoxyeicosatrienoic acids (EETs) by preventing their degradation to the biologically inactive dihydroxyeicosatrienoic acids (DHETEs) using blockade of soluble epoxide hydrolase (sEH) would atte...
Autores principales: | Kujal, Petr, Čertíková Chábová, Vera, Škaroupková, Petra, Husková, Zuzana, Vernerová, Zdena, Kramer, Herbert J, Walkowska, Agnieszka, Kompanowska-Jezierska, Elzbieta, Sadowski, Janusz, Kitada, Kento, Nishiyama, Akira, Hwang, Sung H, Hammock, Bruce D, Imig, John D, Červenka, Ludek |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038339/ https://www.ncbi.nlm.nih.gov/pubmed/24471737 http://dx.doi.org/10.1111/1440-1681.12204 |
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