Cargando…
Lamin B2 prevents chromosome instability by ensuring proper mitotic chromosome segregation
The majority of human cancer shows chromosomal instability (CIN). Although the precise mechanism remains largely uncertain, proper progression of mitosis is crucial. B-type lamins were suggested to be components of the spindle matrix of mitotic cells and to be involved in mitotic spindle assembly; t...
| Autores principales: | , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2014
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038388/ https://www.ncbi.nlm.nih.gov/pubmed/24637494 http://dx.doi.org/10.1038/oncsis.2014.6 |