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Severity of cough in idiopathic pulmonary fibrosis is associated with MUC5 B genotype

BACKGROUND: A polymorphism (rs35705950) in the promoter region of the mucin MUC5B is associated with both familial and sporadic forms of idiopathic pulmonary fibrosis. (IPF) We hypothesize that this common MUC5B variant will impact the expression of cough, a frequent disabling symptom seen in subjec...

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Detalles Bibliográficos
Autores principales:	Scholand, Mary Beth, Wolff, Roger, Crossno, Peter Fredrick, Sundar, Krishna, Winegar, Molly, Whipple, Spencer, Carey, Patrick, Sunchild, Nicholas, Coon, Hilary
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038402/ https://www.ncbi.nlm.nih.gov/pubmed/24667072 http://dx.doi.org/10.1186/1745-9974-10-3

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