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The Proper Splicing of RNAi Factors Is Critical for Pericentric Heterochromatin Assembly in Fission Yeast
Heterochromatin preferentially assembles at repetitive DNA elements, playing roles in transcriptional silencing, recombination suppression, and chromosome segregation. The RNAi machinery is required for heterochromatin assembly in a diverse range of organisms. In fission yeast, RNA splicing factors...
Autores principales: | Kallgren, Scott P., Andrews, Stuart, Tadeo, Xavier, Hou, Haitong, Moresco, James J., Tu, Patricia G., Yates, John R., Nagy, Peter L., Jia, Songtao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038458/ https://www.ncbi.nlm.nih.gov/pubmed/24874881 http://dx.doi.org/10.1371/journal.pgen.1004334 |
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