Cargando…
PAX6 Regulates Melanogenesis in the Retinal Pigmented Epithelium through Feed-Forward Regulatory Interactions with MITF
During organogenesis, PAX6 is required for establishment of various progenitor subtypes within the central nervous system, eye and pancreas. PAX6 expression is maintained in a variety of cell types within each organ, although its role in each lineage and how it acquires cell-specific activity remain...
Autores principales: | Raviv, Shaul, Bharti, Kapil, Rencus-Lazar, Sigal, Cohen-Tayar, Yamit, Schyr, Rachel, Evantal, Naveh, Meshorer, Eran, Zilberberg, Alona, Idelson, Maria, Reubinoff, Benjamin, Grebe, Rhonda, Rosin-Arbesfeld, Rina, Lauderdale, James, Lutty, Gerard, Arnheiter, Heinz, Ashery-Padan, Ruth |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038462/ https://www.ncbi.nlm.nih.gov/pubmed/24875170 http://dx.doi.org/10.1371/journal.pgen.1004360 |
Ejemplares similares
-
The LHX2-OTX2 transcriptional regulatory module controls retinal pigmented epithelium differentiation and underlies genetic risk for age-related macular degeneration
por: Cohen-Gulkar, Mazal, et al.
Publicado: (2023) -
MITF—the first 25 years
por: Goding, Colin R., et al.
Publicado: (2019) -
The EDD E3 ubiquitin ligase ubiquitinates and up-regulates β-catenin
por: Hay-Koren, Avital, et al.
Publicado: (2011) -
Endothelin-1 enhances the melanogenesis via MITF-GPNMB pathway
por: Zhang, Ping, et al.
Publicado: (2013) -
Wnt ligands from the embryonic surface ectoderm regulate ‘bimetallic strip’ optic cup morphogenesis in mouse
por: Carpenter, April C., et al.
Publicado: (2015)