Safety and Efficacy Assessment of Two New Leprosy Skin Test Antigens: Randomized Double Blind Clinical Study

BACKGROUND: New tools are required for the diagnosis of pre-symptomatic leprosy towards further reduction of disease burden and its associated reactions. To address this need, two new skin test antigens were developed to assess safety and efficacy in human trials. METHODS: A Phase I safety trial was...

Descripción completa

Detalles Bibliográficos
Autores principales: Rivoire, Becky L., Groathouse, Nathan A., TerLouw, Stephen, Neupane, Kapil Dev, Ranjit, Chaman, Sapkota, Bishwa Raj, Khadge, Saraswoti, Kunwar, Chatra B., Macdonald, Murdo, Hawksworth, Rachel, Thapa, Min B., Hagge, Deanna A., Tibbals, Melinda, Smith, Carol, Dube, Tina, She, Dewei, Wolff, Mark, Zhou, Eric, Makhene, Mamodikoe, Mason, Robin, Sizemore, Christine, Brennan, Patrick J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038488/
https://www.ncbi.nlm.nih.gov/pubmed/24874401
http://dx.doi.org/10.1371/journal.pntd.0002811

Ejemplares similares

Ejemplares similares