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NeuroD1 mediates nicotine-induced migration and invasion via regulation of the nicotinic acetylcholine receptor subunits in a subset of neural and neuroendocrine carcinomas
Cigarette smoking is a major risk factor for acquisition of small cell lung cancer (SCLC). A role has been demonstrated for the basic helix-loop-helix transcription factor NeuroD1 in the pathogenesis of neural and neuroendocrine lung cancer, including SCLC. In the present study we investigate the po...
Autores principales: | Osborne, Jihan K., Guerra, Marcy L., Gonzales, Joshua X., McMillan, Elizabeth A., Minna, John D., Cobb, Melanie H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038504/ https://www.ncbi.nlm.nih.gov/pubmed/24719457 http://dx.doi.org/10.1091/mbc.E13-06-0316 |
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