SIRT1 Mediates FOXA2 Breakdown by Deacetylation in a Nutrient-Dependent Manner

The Forkhead transcription factor FOXA2 plays a fundamental role in controlling metabolic homeostasis in the liver during fasting. The precise molecular regulation of FOXA2 in response to nutrients is not fully understood. Here, we studied whether FOXA2 could be controlled at a post-translational le...

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Detalles Bibliográficos
Autores principales: van Gent, Rogier, Di Sanza, Claudio, van den Broek, Niels J. F., Fleskens, Veerle, Veenstra, Aukje, Stout, Gerdine J., Brenkman, Arjan B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038515/
https://www.ncbi.nlm.nih.gov/pubmed/24875183
http://dx.doi.org/10.1371/journal.pone.0098438

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038515/
https://www.ncbi.nlm.nih.gov/pubmed/24875183
http://dx.doi.org/10.1371/journal.pone.0098438

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