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SIRT1 Mediates FOXA2 Breakdown by Deacetylation in a Nutrient-Dependent Manner
The Forkhead transcription factor FOXA2 plays a fundamental role in controlling metabolic homeostasis in the liver during fasting. The precise molecular regulation of FOXA2 in response to nutrients is not fully understood. Here, we studied whether FOXA2 could be controlled at a post-translational le...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038515/ https://www.ncbi.nlm.nih.gov/pubmed/24875183 http://dx.doi.org/10.1371/journal.pone.0098438 |