Blood cis-eQTL Analysis Fails to Identify Novel Association Signals among Sub-Threshold Candidates from Genome-Wide Association Studies in Restless Legs Syndrome

Restless legs syndrome (RLS) is a common neurologic disorder characterized by nightly dysesthesias affecting the legs primarily during periods of rest and relieved by movement. RLS is a complex genetic disease and susceptibility factors in six genomic regions have been identified by means of genome-...

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Detalles Bibliográficos
Autores principales: Schulte, Eva C., Schramm, Katharina, Schurmann, Claudia, Lichtner, Peter, Herder, Christian, Roden, Michael, Gieger, Christian, Peters, Annette, Trenkwalder, Claudia, Högl, Birgit, Frauscher, Birgit, Berger, Klaus, Fietze, Ingo, Gross, Nadine, Stiasny-Kolster, Karin, Oertel, Wolfgang, Bachmann, Cornelius G., Paulus, Walter, Zimprich, Alexander, Völzke, Henry, Schminke, Ulf, Nauck, Matthias, Illig, Thomas, Meitinger, Thomas, Müller-Myhsok, Bertram, Prokisch, Holger, Winkelmann, Juliane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038519/
https://www.ncbi.nlm.nih.gov/pubmed/24875634
http://dx.doi.org/10.1371/journal.pone.0098092

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