The Inflammasome Pyrin Contributes to Pertussis Toxin-Induced IL-1β Synthesis, Neutrophil Intravascular Crawling and Autoimmune Encephalomyelitis

Microbial agents can aggravate inflammatory diseases, such as multiple sclerosis (MS) and its animal model, experimental autoimmune encephalomyelitis (EAE). An example is pertussis toxin (PTX), a bacterial virulence factor commonly used as an adjuvant to promote EAE, but whose mechanism of action is...

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Detalles Bibliográficos
Autores principales: Dumas, Aline, Amiable, Nathalie, de Rivero Vaccari, Juan Pablo, Chae, Jae Jin, Keane, Robert W., Lacroix, Steve, Vallières, Luc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038594/
https://www.ncbi.nlm.nih.gov/pubmed/24875775
http://dx.doi.org/10.1371/journal.ppat.1004150

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