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Bacterial Superantigens Promote Acute Nasopharyngeal Infection by Streptococcus pyogenes in a Human MHC Class II-Dependent Manner
Establishing the genetic determinants of niche adaptation by microbial pathogens to specific hosts is important for the management and control of infectious disease. Streptococcus pyogenes is a globally prominent human-specific bacterial pathogen that secretes superantigens (SAgs) as ‘trademark’ vir...
Autores principales: | Kasper, Katherine J., Zeppa, Joseph J., Wakabayashi, Adrienne T., Xu, Stacey X., Mazzuca, Delfina M., Welch, Ian, Baroja, Miren L., Kotb, Malak, Cairns, Ewa, Cleary, P. Patrick, Haeryfar, S. M. Mansour, McCormick, John K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038607/ https://www.ncbi.nlm.nih.gov/pubmed/24875883 http://dx.doi.org/10.1371/journal.ppat.1004155 |
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