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Dynamics of HIV Latency and Reactivation in a Primary CD4+ T Cell Model
HIV latency is a major obstacle to curing infection. Current strategies to eradicate HIV aim at increasing transcription of the latent provirus. In the present study we observed that latently infected CD4+ T cells from HIV-infected individuals failed to produce viral particles upon ex vivo exposure...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038609/ https://www.ncbi.nlm.nih.gov/pubmed/24875931 http://dx.doi.org/10.1371/journal.ppat.1004156 |