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Altered Immunohistochemical Expression of Mast Cell Tryptase and Chymase in the Pathogenesis of Oral Submucous Fibrosis and Malignant Transformation of the Overlying Epithelium

Mast cells (MCs) expressing serine proteases; tryptase and chymase, are associated with fibrosis in various diseases. However, little is known about their involvement in oral submucous fibrosis (OSF). Our goal was to evaluate the role of MC tryptase and chymase in the pathogenesis of OSF and its mal...

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Detalles Bibliográficos
Autores principales: Yadav, Archana, Desai, Rajiv S., Bhuta, Bansari A., Singh, Jatinder S., Mehta, Reema, Nehete, Akash P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038611/
https://www.ncbi.nlm.nih.gov/pubmed/24874976
http://dx.doi.org/10.1371/journal.pone.0098719