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Targeted Radionuclide Therapy with A (177)Lu-labeled Anti-HER2 Nanobody
RIT has become an attractive strategy in cancer treatment, but still faces important drawbacks due to poor tumor penetration and undesirable pharmacokinetics of the targeting vehicles. Smaller radiolabeled antibody fragments and peptides feature highly specific target accumulation, resulting in low...
Autores principales: | D'Huyvetter, Matthias, Vincke, Cécile, Xavier, Catarina, Aerts, An, Impens, Nathalie, Baatout, Sarah, De Raeve, Hendrik, Muyldermans, Serge, Caveliers, Vicky, Devoogdt, Nick, Lahoutte, Tony |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038753/ https://www.ncbi.nlm.nih.gov/pubmed/24883121 http://dx.doi.org/10.7150/thno.8156 |
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