Luminescent Dual Sensors Reveal Extracellular pH-Gradients and Hypoxia on Chronic Wounds That Disrupt Epidermal Repair

Wound repair is a quiescent mechanism to restore barriers in multicellular organisms upon injury. In chronic wounds, however, this program prematurely stalls. It is known that patterns of extracellular signals within the wound fluid are crucial to healing. Extracellular pH (pH(e)) is precisely regul...

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Detalles Bibliográficos
Autores principales: Schreml, Stephan, Meier, Robert J., Kirschbaum, Michael, Kong, Su Chii, Gehmert, Sebastian, Felthaus, Oliver, Küchler, Sarah, Sharpe, Justin R., Wöltje, Kerstin, Weiß, Katharina T., Albert, Markus, Seidl, Uwe, Schröder, Josef, Morsczeck, Christian, Prantl, Lukas, Duschl, Claus, Pedersen, Stine F., Gosau, Martin, Berneburg, Mark, Wolfbeis, Otto S., Landthaler, Michael, Babilas, Philipp
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038754/
https://www.ncbi.nlm.nih.gov/pubmed/24883122
http://dx.doi.org/10.7150/thno.9052

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