Full-Genome Sequence of Human Betacoronavirus 2c Jordan-N3/2012 after Serial Passage in Mammalian Cells

Middle East respiratory syndrome coronavirus (MERS-CoV) is the etiologic agent of a highly lethal pneumonia. Here, we report the full-genome sequence of the Jordan-N3/2012 strain after serial passage in two distinct mammalian cell lines. The genome exhibits noteworthy stability, which may inform the...

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Autores principales: Frey, Kenneth G., Redden, Cassie L., Bishop-Lilly, Kimberly A., Johnson, Reed, Hensley, Lisa E., Raviprakash, Kanakatte, Luke, Thomas, Kochel, Tad, Mokashi, Vishwesh P., Defang, Gabriel N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2014
Materias:
Viruses
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038873/
https://www.ncbi.nlm.nih.gov/pubmed/24874668
http://dx.doi.org/10.1128/genomeA.00324-14
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author Frey, Kenneth G.
Redden, Cassie L.
Bishop-Lilly, Kimberly A.
Johnson, Reed
Hensley, Lisa E.
Raviprakash, Kanakatte
Luke, Thomas
Kochel, Tad
Mokashi, Vishwesh P.
Defang, Gabriel N.
author_facet Frey, Kenneth G.
Redden, Cassie L.
Bishop-Lilly, Kimberly A.
Johnson, Reed
Hensley, Lisa E.
Raviprakash, Kanakatte
Luke, Thomas
Kochel, Tad
Mokashi, Vishwesh P.
Defang, Gabriel N.
author_sort Frey, Kenneth G.
collection PubMed
description Middle East respiratory syndrome coronavirus (MERS-CoV) is the etiologic agent of a highly lethal pneumonia. Here, we report the full-genome sequence of the Jordan-N3/2012 strain after serial passage in two distinct mammalian cell lines. The genome exhibits noteworthy stability, which may inform the development of vaccines and therapeutics used to treat infection with this virus.
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spelling pubmed-40388732014-06-06 Full-Genome Sequence of Human Betacoronavirus 2c Jordan-N3/2012 after Serial Passage in Mammalian Cells Frey, Kenneth G. Redden, Cassie L. Bishop-Lilly, Kimberly A. Johnson, Reed Hensley, Lisa E. Raviprakash, Kanakatte Luke, Thomas Kochel, Tad Mokashi, Vishwesh P. Defang, Gabriel N. Genome Announc Viruses Middle East respiratory syndrome coronavirus (MERS-CoV) is the etiologic agent of a highly lethal pneumonia. Here, we report the full-genome sequence of the Jordan-N3/2012 strain after serial passage in two distinct mammalian cell lines. The genome exhibits noteworthy stability, which may inform the development of vaccines and therapeutics used to treat infection with this virus. American Society for Microbiology 2014-05-29 /pmc/articles/PMC4038873/ /pubmed/24874668 http://dx.doi.org/10.1128/genomeA.00324-14 Text en Copyright © 2014 Frey et al. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution 3.0 Unported license (http://creativecommons.org/licenses/by/3.0/) .
spellingShingle Viruses
Frey, Kenneth G.
Redden, Cassie L.
Bishop-Lilly, Kimberly A.
Johnson, Reed
Hensley, Lisa E.
Raviprakash, Kanakatte
Luke, Thomas
Kochel, Tad
Mokashi, Vishwesh P.
Defang, Gabriel N.
Full-Genome Sequence of Human Betacoronavirus 2c Jordan-N3/2012 after Serial Passage in Mammalian Cells
title Full-Genome Sequence of Human Betacoronavirus 2c Jordan-N3/2012 after Serial Passage in Mammalian Cells
title_full Full-Genome Sequence of Human Betacoronavirus 2c Jordan-N3/2012 after Serial Passage in Mammalian Cells
title_fullStr Full-Genome Sequence of Human Betacoronavirus 2c Jordan-N3/2012 after Serial Passage in Mammalian Cells
title_full_unstemmed Full-Genome Sequence of Human Betacoronavirus 2c Jordan-N3/2012 after Serial Passage in Mammalian Cells
title_short Full-Genome Sequence of Human Betacoronavirus 2c Jordan-N3/2012 after Serial Passage in Mammalian Cells
title_sort full-genome sequence of human betacoronavirus 2c jordan-n3/2012 after serial passage in mammalian cells
topic Viruses
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038873/
https://www.ncbi.nlm.nih.gov/pubmed/24874668
http://dx.doi.org/10.1128/genomeA.00324-14
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