Duplication of TBK1 Stimulates Autophagy in iPSC-derived Retinal Cells from a Patient with Normal Tension Glaucoma

Duplication of theTBK1 gene causes normal tension glaucoma (NTG); however the mechanism by which this copy number variation leads to retinal ganglion cell death is poorly understood. The ability to use skin-derived induced pluripotent stem cells (iPSCs) to investigate the function or dysfunction of...

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Detalles Bibliográficos
Autores principales: Tucker, Budd A., Solivan-Timpe, Frances, Roos, Ben R., Anfinson, Kristin R., Robin, Alan L., Wiley, Luke A., Mullins, Robert F., Fingert, John H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038935/
https://www.ncbi.nlm.nih.gov/pubmed/24883232
http://dx.doi.org/10.4172/2157-7633.1000161

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038935/
https://www.ncbi.nlm.nih.gov/pubmed/24883232
http://dx.doi.org/10.4172/2157-7633.1000161

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