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The immunocytokine NHS-IL12 as a potential cancer therapeutic

Targeted delivery of IL-12 might turn this cytokine into a safer, more effective cancer therapeutic. Here we describe a novel immunocytokine, NHS-IL12, consisting of two molecules of IL-12 fused to a tumor necrosis-targeting human IgG1 (NHS76). The addition of the human IgG1 moiety resulted in a lon...

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Detalles Bibliográficos
Autores principales:	Fallon, Jonathan, Tighe, Robert, Kradjian, Giorgio, Guzman, Wilson, Bernhardt, Anna, Neuteboom, Berend, Lan, Yan, Sabzevari, Helen, Schlom, Jeffrey, Greiner, John W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2014
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039112/ https://www.ncbi.nlm.nih.gov/pubmed/24681847

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