Cargando…

Diffuse large B-cell lymphoma with combined TP53 mutation and MIR34A methylation: Another “double hit” lymphoma with very poor outcome?

MiR34A, B and C have been implicated in lymphomagenesis, but information on their role in normal CD19+ B-cells (PBL-B) and de novo diffuse large B-cell lymphoma (DLBCL) is limited. We show that in normal and activated B-cells miR34A-5p plays a dominant role compared to other miR34 family members. On...

Descripción completa

Detalles Bibliográficos
Autores principales:	Asmar, Fazila, Hother, Christoffer, Kulosman, Gorjan, Treppendahl, Marianne Bach, Nielsen, Helene Myrtue, Ralfkiaer, Ulrik, Pedersen, Anja, Møller, Michael Boe, Ralfkiaer, Elisabeth, de Nully Brown, Peter, Grønbæk, Kirsten
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2014
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039115/ https://www.ncbi.nlm.nih.gov/pubmed/24722400

Ejemplares similares

Investigation of MGMT and DAPK1 methylation patterns in diffuse large B-cell lymphoma using allelic MSP-pyrosequencing
por: Kristensen, Lasse Sommer, et al.
Publicado: (2013)

Development and Blind Clinical Validation of a MicroRNA Based Predictor of Response to Treatment with R-CHO(E)P in DLBCL
por: Knudsen, Steen, et al.
Publicado: (2015)

TP53 hotspot mutations are predictive of survival in primary central nervous system lymphoma patients treated with combination chemotherapy
por: Munch-Petersen, Helga D., et al.
Publicado: (2016)

Hypermethylation of DAPK1 is an independent prognostic factor predicting survival in diffuse large B-cell lymphoma
por: Kristensen, Lasse Sommer, et al.
Publicado: (2014)

Onco-miR-155 targets SHIP1 to promote TNFα-dependent growth of B cell lymphomas
por: Pedersen, Irene M, et al.
Publicado: (2009)

Equitoxic Doses of 5-Azacytidine and 5-Aza-2′Deoxycytidine Induce Diverse Immediate and Overlapping Heritable Changes in the Transcriptome
por: Qiu, Xiangning, et al.
Publicado: (2010)

SOX11 and TP53 add prognostic information to MIPI in a homogenously treated cohort of mantle cell lymphoma – a Nordic Lymphoma Group study
por: Nordström, Lena, et al.
Publicado: (2014)

The value of circulating microRNAs for early diagnosis of B-cell lymphoma: A case-control study on historical samples
por: Jørgensen, Steffen, et al.
Publicado: (2020)

Malignant T cells express lymphotoxin α and drive endothelial activation in cutaneous T cell lymphoma
por: Lauenborg, Britt, et al.
Publicado: (2015)

TP53 Gene Status Affects Survival in Advanced Mycosis Fungoides
por: Wooler, Gitte, et al.
Publicado: (2016)

Evaluation of bcl-2 protein expression and 14;18 translocation as prognostic markers in follicular lymphoma.
por: Pezzella, F., et al.
Publicado: (1992)

Profiling of ribose methylations in ribosomal RNA from diffuse large B-cell lymphoma patients for evaluation of ribosomes as drug targets
por: Krogh, Nicolai, et al.
Publicado: (2020)

Prognostic significance of the therapeutic targets histone deacetylase 1, 2, 6 and acetylated histone H4 in cutaneous T-cell lymphoma
por: Marquard, L, et al.
Publicado: (2008)

The value of immunocytochemical methods in the differential diagnosis of anaplastic thyroid tumours.
por: Ralfkiaer, N., et al.
Publicado: (1985)

Antibody BNH9 detects red blood cell-related antigens on anaplastic large cell (CD30+) lymphomas.
por: Delsol, G., et al.
Publicado: (1991)

Advancing the management of double hit lymphoma
por: Landsburg, Daniel J.
Publicado: (2017)

Drug therapy for double-hit lymphoma
por: Phuoc, Vania, et al.
Publicado: (2019)

Return to work for patients with diffuse large B-cell lymphoma and transformed indolent lymphoma undergoing autologous stem cell transplantation
por: Arboe, Bente, et al.
Publicado: (2017)

Tolosa-Hunt Syndrome in Double-Hit Lymphoma
por: Peddi, Prakash, et al.
Publicado: (2015)

Rational targeted therapeutics for double-hit lymphoma
por: Azizian, Nancy G, et al.
Publicado: (2019)

Big Bang machine hit with another delay
Publicado: (2009)

Big Bang machine hit with another delay
Publicado: (2009)

Big Bang machine hit with another delay
Publicado: (2009)

Big Bang machine hit with another delay
Publicado: (2009)

Altered pathways and targeted therapy in double hit lymphoma
por: Zhuang, Yuxin, et al.
Publicado: (2022)

Flow Cytometric Evaluation of Double/Triple Hit Lymphoma
por: Roth, Christine G., et al.
Publicado: (2016)

p53 is associated with high‐risk and pinpoints TP53 missense mutations in mantle cell lymphoma
por: Rodrigues, Joana M., et al.
Publicado: (2020)

The Danish National Lymphoma Registry: Coverage and Data Quality
por: Arboe, Bente, et al.
Publicado: (2016)

Double-hit lymphoma of the male breast: a case report
por: Elgaafary, Shaymaa, et al.
Publicado: (2020)

Transformation of double-hit follicular lymphoma to plasmablastic lymphoma: a partial role of MYC gene rearrangement
por: Ise, Mikiko, et al.
Publicado: (2018)

Aberrant methylation of cell-free circulating DNA in plasma predicts poor outcome in diffuse large B cell lymphoma
por: Kristensen, Lasse Sommer, et al.
Publicado: (2016)

Sexual dysfunction is highly prevalent in male survivors of malignant lymphoma
por: Micas Pedersen, Signe, et al.
Publicado: (2023)

Dose-adjusted EPOCH and rituximab for the treatment of double expressor and double-hit diffuse large B-cell lymphoma: impact of TP53 mutations on clinical outcome
por: Dodero, Anna, et al.
Publicado: (2021)

Sinonasal B‐cell lymphomas: A nationwide cohort study, with an emphasis on the prognosis and the recurrence pattern of primary diffuse large B‐cell lymphoma
por: Eriksen, Patrick R. G., et al.
Publicado: (2022)

Diagnostic Approach for Double-Hit and Triple-Hit Lymphoma Based on Immunophenotypic and Cytogenetic Characteristics of Bone Marrow Specimens
por: Kim, Heyjin, et al.
Publicado: (2020)

Peripheral immune cell profiling of double-hit lymphoma by mass cytometry
por: Lei, Tao, et al.
Publicado: (2023)

Cell‐of‐origin determined by both gene expression profiling and immunohistochemistry is the strongest predictor of survival in patients with diffuse large B‐cell lymphoma
por: Abdulla, Maysaa, et al.
Publicado: (2019)

MYC/BCL2/BCL6 triple hit and TP53 deletion in a case of high-grade B cell lymphoma receiving CAR T cell immunotherapy
por: Wang, Jiachen, et al.
Publicado: (2021)

Publisher Correction: Epigenetic changes in myelofibrosis: Distinct methylation changes in the myeloid compartments and in cases with ASXL1 mutations
por: Nielsen, Helene Myrtue, et al.
Publicado: (2018)

Epigenetic changes in myelofibrosis: Distinct methylation changes in the myeloid compartments and in cases with ASXL1 mutations
por: Nielsen, Helene Myrtue, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_vn1gl0iqeov8u1j4av994sva6a