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Polyubiquitylation of AMF requires cooperation between the gp78 and TRIM25 ubiquitin ligases
gp78 is a ubiquitin ligase that plays a vital role in endoplasmic reticulum (ER)-associated degradation (ERAD). Here we report that autocrine motility factor (AMF), also known as phosphoglucose isomerase (PGI), is a novel substrate of gp78. We show that polyubiquitylation of AMF requires cooperative...
Autores principales: | Wang, Ying, Ha, Seung-Wook, Zhang, Tianpeng, Kho, Dhong-Hyo, Raz, Avraham, Xie, Youming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039143/ https://www.ncbi.nlm.nih.gov/pubmed/24810856 |
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