ΔN-P63α and TA-P63α exhibit intrinsic differences in transactivation specificities that depend on distinct features of DNA target sites

TP63 is a member of the TP53 gene family that encodes for up to ten different TA and ΔN isoforms through alternative promoter usage and alternative splicing. Besides being a master regulator of gene expression for squamous epithelial proliferation, differentiation and maintenance, P63, through diffe...

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Detalles Bibliográficos
Autores principales: Monti, Paola, Ciribilli, Yari, Bisio, Alessandra, Foggetti, Giorgia, Raimondi, Ivan, Campomenosi, Paola, Menichini, Paola, Fronza, Gilberto, Inga, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039150/
https://www.ncbi.nlm.nih.gov/pubmed/24926492

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