MiR-214 and N-ras regulatory loop suppresses rhabdomyosarcoma cell growth and xenograft tumorigenesis

Rhabdomyosarcoma (RMS) is a childhood malignant soft tissue cancer that is derived from myogenic progenitors trapped in a permanent mode of growth. Here, we report that miR-214 is markedly down-regulated in human RMS cell lines. Although not required for embryogenesis in mice, miR-214 suppresses mou...

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Detalles Bibliográficos
Autores principales: Huang, Hui-jie, Liu, Jun, Hua, Hu, Li, San-en, Zhao, Jin, Yue, Shen, Yu, Ting-ting, Jin, Yu-cui, Cheng, Steven Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039153/
https://www.ncbi.nlm.nih.gov/pubmed/24811402

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