Extracellular activation of Wnt signaling through epigenetic dysregulation of Wnt inhibitory factor-1 (Wif-1) is associated with pathogenesis of adrenocortical tumor

Wnt/β-catenin signaling is considered to be an essential regulator of adrenocortical oncogenesis. Wnt inhibitory factor-1 (Wif-1), an extracellular regulator of Wnt signaling, is frequently down-regulated by hypermethylation of the promoter CpG. We investigated epigenetic regulation of Wif-1 and its...

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Detalles Bibliográficos
Autores principales: Mitsui, Yozo, Yasumoto, Hiroaki, Nagami, Taichi, Hiraki, Miho, Arichi, Naoko, Ishikawa, Noriyoshi, Araki, Asuka, Maruyama, Riruke, Tanaka, Yuichiro, Dahiya, Rajvir, Shiina, Hiroaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039156/
https://www.ncbi.nlm.nih.gov/pubmed/24755523

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