Cargando…

Aurora-A signaling is activated in advanced stage of squamous cell carcinoma of head and neck cancer and requires osteopontin to stimulate invasive behavior

The clinical significances, cellular effects, and molecular mechanisms by which Aurora-A mediate its invasive effects in HNSCC are still unclear. Here, we found that Aurora-A expression is significantly higher in tumor tissues on 14-microarray of HNSCC in Oncomine-databases. The activity of Aurora-A...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chien, Chih-Yen, Tsai, Hsin-Ting, Su, Li-Jen, Chuang, Hui-Ching, Shiu, Li-Yen, Huang, Chao-Cheng, Fang, Fu-Min, Yu, Chun-Chieh, Su, Huei-Ting, Chen, Chang-Han
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2014
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039160/ https://www.ncbi.nlm.nih.gov/pubmed/24810160

Ejemplares similares

Suppression of Aurora-A-FLJ10540 signaling axis prohibits the malignant state of head and neck cancer
por: Chen, Chang-Han, et al.
Publicado: (2015)

Metformin disrupts malignant behavior of oral squamous cell carcinoma via a novel signaling involving Late SV40 factor/Aurora-A
por: Chen, Chang-Han, et al.
Publicado: (2017)

Osteopontin Levels in Patients with Squamous Metastatic Head and Neck Cancer
por: Maleš, Josip, et al.
Publicado: (2021)

Targeting mTOR-CCL20 Signaling May Improve Response to Docetaxel in Head and Neck Squamous Cell Carcinoma
por: Chou, Ming-Huei, et al.
Publicado: (2021)

Osteopontin Involves Cisplatin Resistance and Poor Prognosis in Oral Squamous Cell Carcinoma
por: Luo, Sheng-Dean, et al.
Publicado: (2015)

High ERCC1 expression predicts cisplatin-based chemotherapy resistance and poor outcome in unresectable squamous cell carcinoma of head and neck in a betel-chewing area
por: Chiu, Tai-Jan, et al.
Publicado: (2011)

DRP1 contributes to head and neck cancer progression and induces glycolysis through modulated FOXM1/MMP12 axis
por: Huang, Tai‐Lin, et al.
Publicado: (2022)

Validation of the Chinese Version of the Shame and Stigma Scale in Patients with Head and Neck Cancer
por: Tseng, Wei-Ting, et al.
Publicado: (2019)

Stereotactic body radiotherapy plus cetuximab for previously irradiated un-resectable head and neck cancer
por: Huang, Tai-Lin, et al.
Publicado: (2022)

FLJ10540 is associated with tumor progression in nasopharyngeal carcinomas and contributes to nasopharyngeal cell proliferation, and metastasis via osteopontin/CD44 pathway
por: Chen, Chang-Han, et al.
Publicado: (2012)

Aurora Kinase Inhibition Overcomes Cetuximab Resistance in Squamous Cell Cancer of the Head and Neck
por: Hoellein, Alexander, et al.
Publicado: (2011)

Treatment Outcomes of Patients with Locally Advanced Synchronous Esophageal and Head/Neck Squamous Cell Carcinoma Receiving Curative Concurrent Chemoradiotherapy
por: Chen, Yen-Hao, et al.
Publicado: (2017)

Clinical impact of albumin in advanced head and neck cancer patients with free flap reconstruction—a retrospective study
por: Tsai, Ming-Hsien, et al.
Publicado: (2018)

7-Epitaxol Induces Apoptosis and Autophagy in Head and Neck Squamous Cell Carcinoma through Inhibition of the ERK Pathway
por: Kumar, V. Bharath, et al.
Publicado: (2021)

The response of head and neck squamous cell carcinoma to cetuximab treatment depends on Aurora kinase A polymorphism
por: Pickhard, Anja, et al.
Publicado: (2014)

The role of vein grafts in reconstructive head and neck microsurgery
por: Lai, Chih-Sheng, et al.
Publicado: (2021)

Effects of Exercise in Patients Undergoing Chemotherapy for Head and Neck Cancer: A Pilot Randomized Controlled Trial
por: Lin, Kuan-Yin, et al.
Publicado: (2021)

Efficacy of Different Chemotherapy Regimens in Patients with Locally Advanced Synchronous Esophageal and Head/Neck Squamous Cell Carcinoma Receiving Curative Concurrent Chemoradiotherapy
por: Chen, Yen-Hao, et al.
Publicado: (2020)

PI3k inhibitors (BKM120 and BYL719) as radiosensitizers for head and neck squamous cell carcinoma during radiotherapy
por: Chuang, Fu-Cheng, et al.
Publicado: (2021)

Prediction of extranodal extension in head and neck squamous cell carcinoma by CT images using an evolutionary learning model
por: Huang, Tzu-Ting, et al.
Publicado: (2023)

Low p16 Cytoplasmic Staining Predicts Poor Treatment Outcome in Patients with p16-Negative Locally Advanced Head and Neck Squamous Cell Carcinoma Receiving TPF Induction Chemotherapy
por: Chen, Yen-Hao, et al.
Publicado: (2023)

Targeting PI3K/AKT/mTOR Signaling Pathway as a Radiosensitization in Head and Neck Squamous Cell Carcinomas
por: Su, Yu-Chieh, et al.
Publicado: (2022)

Mammalian target of rapamycin and head and neck squamous cell carcinoma
por: Liao, Yu-Min, et al.
Publicado: (2011)

Serum Levels of Stromal Cell-Derived Factor-1α and Vascular Endothelial Growth Factor Predict Clinical Outcomes in Head and Neck Squamous Cell Carcinoma Patients Receiving TPF Induction Chemotherapy
por: Chen, Yen-Hao, et al.
Publicado: (2022)

Evaluation of Objective and Subjective Swallowing Outcomes in Patients with Dysphagia Treated for Head and Neck Cancer
por: Liou, Hsin-Hao, et al.
Publicado: (2022)

6-shogaol is a potential treatment for Head and Neck Squamous Cell Carcinoma
por: Hsu, Cheng-Ming, et al.
Publicado: (2023)

Clinical impact of human papillomavirus in laryngeal squamous cell carcinoma: a retrospective study
por: Chen, Wei-Chih, et al.
Publicado: (2017)

In-Hospital and Long-Term Outcomes in Patients with Head and Neck Cancer Bleeding
por: Yen, Chieh-Ching, et al.
Publicado: (2022)

A Novel Hydroxamate-Based Compound WMJ-J-09 Causes Head and Neck Squamous Cell Carcinoma Cell Death via LKB1-AMPK-p38MAPK-p63-Survivin Cascade
por: Yen, Chia-Sheng, et al.
Publicado: (2018)

Role of JNK activation in paclitaxel-induced apoptosis in human head and neck squamous cell carcinoma
por: Lan, Yu-Yan, et al.
Publicado: (2021)

Risk factors for rebleeding and long-term outcomes in patients with head and neck cancer bleeding: a multicenter study
por: Wang, Chih-Kai, et al.
Publicado: (2022)

An integrated analysis of dysregulated SCD1 in human cancers and functional verification of miR-181a-5p/SCD1 axis in esophageal squamous cell carcinoma
por: Wang, Bing-Yen, et al.
Publicado: (2023)

Risk Prediction Models for Patients with Head and Neck Cancer among the Taiwanese Population
por: Yu, Ming-Zhen, et al.
Publicado: (2022)

Betel nut chewing history is an independent prognosticator for smoking patients with locally advanced stage IV head and neck squamous cell carcinoma receiving induction chemotherapy with docetaxel, cisplatin, and fluorouracil
por: Su, Yan-Ye, et al.
Publicado: (2016)

The Aurora-Kinase A Phe31-Ile polymorphism as possible predictor of response to treatment in head and neck squamous cell carcinoma
por: Baumann, Alexander, et al.
Publicado: (2018)

Picrasidine J, a Dimeric β-Carboline-Type Alkaloid from Picrasma quassioides, Inhibits Metastasis of Head and Neck Squamous Cell Carcinoma
por: Ho, Hsin-Yu, et al.
Publicado: (2023)

Aurora kinases shed light on resistance to EGFR inhibition in head and neck cancer
por: Kim, Donghwa, et al.
Publicado: (2021)

Cytokine profiling in plasma distinguishes the histological inflammatory subtype of head and neck squamous cell carcinoma and a novel regulatory role of osteopontin
por: Ghita, Ioana, et al.
Publicado: (2022)

Discovery and Synthesis of a Pyrimidine-Based Aurora Kinase Inhibitor to Reduce Levels of MYC Oncoproteins
por: Chi, Ya-Hui, et al.
Publicado: (2021)

5-Methoxytryptophan Sensitizing Head and Neck Squamous Carcinoma Cell to Cisplatitn Through Inhibiting Signal Transducer and Activator of Transcription 3 (STAT3)
por: Su, Yu-Chieh, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_4gvk26fpa78u6n3oidef7r0ki5