Atg7- and Keap1-dependent autophagy protects breast cancer cell lines against mitoquinone-induced oxidative stress

The interplay between oxidative stress and autophagy is critical for determining the fate of cancer cells exposed to redox-active and cytotoxic chemotherapeutic agents. Mitoquinone (MitoQ), a mitochondrially-targeted redox-active ubiquinone conjugate, selectively kills breast cancer cells over healt...

Descripción completa

Detalles Bibliográficos
Autores principales: Gonzalez, Yanira, Aryal, Baikuntha, Chehab, Leena, Rao, V. Ashutosh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039229/
https://www.ncbi.nlm.nih.gov/pubmed/24681637

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039229/
https://www.ncbi.nlm.nih.gov/pubmed/24681637

Ejemplares similares