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The receptor for urokinase-plasminogen activator (uPAR) controls plasticity of cancer cell movement in mesenchymal and amoeboid migration style
The receptor for the urokinase plasminogen activator (uPAR) is up-regulated in malignant tumors. Historically the function of uPAR in cancer cell invasion is strictly related to its property to promote uPA-dependent proteolysis of extracellular matrix and to open a path to malignant cells. These fea...
Autores principales: | Margheri, Francesca, Luciani, Cristina, Taddei, Maria Letizia, Giannoni, Elisa, Laurenzana, Anna, Biagioni, Alessio, Chillà, Anastasia, Chiarugi, Paola, Fibbi, Gabriella, Rosso1, Mario Del |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039230/ https://www.ncbi.nlm.nih.gov/pubmed/24681666 |
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