Sulforaphane counteracts aggressiveness of pancreatic cancer driven by dysregulated Cx43-mediated gap junctional intercellular communication

The extreme aggressiveness of pancreatic ductal adenocarcinoma (PDA) has been associated with blocked gap junctional intercellular communication (GJIC) and the presence of cancer stem cells (CSCs). We examined whether disturbed GJIC is responsible for a CSC phenotype in established and primary cance...

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Detalles Bibliográficos
Autores principales: Forster, Tobias, Rausch, Vanessa, Zhang, Yiyao, Isayev, Orkhan, Heilmann, Katharina, Schoensiegel, Frank, Liu, Li, Nessling, Michelle, Richter, Karsten, Labsch, Sabrina, Nwaeburu, Clifford C., Mattern, Juergen, Gladkich, Jury, Giese, Nathalia, Werner, Jens, Schemmer, Peter, Gross, Wolfgang, Gebhard, Martha M., Gerhauser, Clarissa, Schaefer, Michael, Herr, Ingrid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039235/
https://www.ncbi.nlm.nih.gov/pubmed/24742583

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