CaMKII and MEK1/2 inhibition time-dependently modify inflammatory signaling in rat cerebral arteries during organ culture

BACKGROUND: Cerebral ischemia induces transcriptional upregulation of inflammatory genes in the brain parenchyma and in cerebral arteries, thereby contributing to the infarct development. The present study was designed to evaluate the involvement of calcium-calmodulin-dependent protein kinase (CaMKI...

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Detalles Bibliográficos
Autores principales: Waldsee, Roya, Eftekhari, Sajedeh, Ahnstedt, Hilda, Johnson, Leif E, Edvinsson, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039324/
https://www.ncbi.nlm.nih.gov/pubmed/24886705
http://dx.doi.org/10.1186/1742-2094-11-90

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