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Genetically shaping morphology of the filamentous fungus Aspergillus glaucus for production of antitumor polyketide aspergiolide A
BACKGROUND: For filamentous fungi, the basic growth unit of hyphae usually makes it sensitive to shear stress which is generated from mechanical force and dynamic fluid in bioreactor, and it severely decreases microbial productions. The conventional strategies against shear-sensitive conundrum in fu...
Autores principales: | Cai, Menghao, Zhang, Ying, Hu, Wei, Shen, Wei, Yu, Zhenzhong, Zhou, Weiqiang, Jiang, Tao, Zhou, Xiangshan, Zhang, Yuanxing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039328/ https://www.ncbi.nlm.nih.gov/pubmed/24886193 http://dx.doi.org/10.1186/1475-2859-13-73 |
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