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Promoter decoding of transcription factor dynamics involves a trade-off between noise and control of gene expression

Numerous transcription factors (TFs) encode information about upstream signals in the dynamics of their activation, but how downstream genes decode these dynamics remains poorly understood. Using microfluidics to control the nucleocytoplasmic translocation dynamics of the budding yeast TF Msn2, we e...

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Detalles Bibliográficos
Autores principales:	Hansen, Anders S, O’Shea, Erin K
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	European Molecular Biology Organization 2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039373/ https://www.ncbi.nlm.nih.gov/pubmed/24189399 http://dx.doi.org/10.1038/msb.2013.56

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