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Pancreatic Cancer Cell Glycosylation Regulates Cell Adhesion and Invasion through the Modulation of α2β1 Integrin and E-Cadherin Function
In our previous studies we have described that ST3Gal III transfected pancreatic adenocarcinoma Capan-1 and MDAPanc-28 cells show increased membrane expression levels of sialyl-Lewis x (SLe(x)) along with a concomitant decrease in α2,6-sialic acid compared to control cells. Here we have addressed th...
Autores principales: | Bassagañas, Sònia, Carvalho, Sandra, Dias, Ana M., Pérez-Garay, Marta, Ortiz, M. Rosa, Figueras, Joan, Reis, Celso A., Pinho, Salomé S., Peracaula, Rosa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039506/ https://www.ncbi.nlm.nih.gov/pubmed/24878505 http://dx.doi.org/10.1371/journal.pone.0098595 |
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