Loss of miR-638 in vitro promotes cell invasion and a mesenchymal-like transition by influencing SOX2 expression in colorectal carcinoma cells

BACKGROUND: Colorectal carcinoma (CRC) is a major cause of cancer mortality. The aberrant expression of several microRNAs is associated with CRC progression; however, the molecular mechanisms underlying this phenomenon are unclear. METHODS: miR-638 and SRY-box 2 (SOX2) expression levels were detecte...

Descripción completa

Detalles Bibliográficos
Autores principales: Ma, Kelong, Pan, Xiaorong, Fan, Pingsheng, He, Yinghua, Gu, Jun, Wang, Wei, Zhang, Tengyue, Li, Zonghai, Luo, Xiaoying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039649/
https://www.ncbi.nlm.nih.gov/pubmed/24885288
http://dx.doi.org/10.1186/1476-4598-13-118

Ejemplares similares

Ejemplares similares