High-throughput capturing and characterization of mutations in essential genes of Caenorhabditis elegans

BACKGROUND: Essential genes are critical for the development of all organisms and are associated with many human diseases. These genes have been a difficult category to study prior to the availability of balanced lethal strains. Despite the power of targeted mutagenesis, there are limitations in ide...

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Detalles Bibliográficos
Autores principales: Chu, Jeffrey Shih-Chieh, Chua, Shu-Yi, Wong, Kathy, Davison, Ann Marie, Johnsen, Robert, Baillie, David L, Rose, Ann M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039747/
https://www.ncbi.nlm.nih.gov/pubmed/24884423
http://dx.doi.org/10.1186/1471-2164-15-361

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