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Cytokine responsiveness of CD8(+) T cells is a reproducible biomarker for the clinical efficacy of dendritic cell vaccination in glioblastoma patients
BACKGROUND: Immunotherapeutic approaches, such as dendritic cell (DC) vaccination, have emerged as promising strategies in the treatment of glioblastoma. Despite their promise, however, the absence of objective biomarkers and/or immunological monitoring techniques to assess the clinical efficacy of...
Autores principales: | Everson, Richard G, Jin, Richard M, Wang, Xiaoyan, Safaee, Michael, Scharnweber, Rudi, Lisiero, Dominique N, Soto, Horacio, Liau, Linda M, Prins, Robert M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039989/ https://www.ncbi.nlm.nih.gov/pubmed/24883189 http://dx.doi.org/10.1186/2051-1426-2-10 |
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