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Synergic silencing of costimulatory molecules prevents cardiac allograft rejection

BACKGROUND: While substantial progress has been made in blocking acute transplant rejection with the advent of immune suppressive drugs, chronic rejection, mediated primarily by recipient antigen presentation, remains a formidable problem in clinical transplantation. We hypothesized that blocking co...

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Detalles Bibliográficos
Autores principales: Zhang, Xusheng, Liu, Yanling, Zhang, Guangfeng, Shi, Jun, Zhang, Xiao, Zheng, Xiufen, Jiang, Alex T, Zhang, Zhu-Xu, Johnston, Nathan, Siu, King Sun, Chen, Ruiqi, Lian, Dameng, Koos, David, Quan, Douglas, Min, Wei-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4040111/
https://www.ncbi.nlm.nih.gov/pubmed/24886282
http://dx.doi.org/10.1186/1479-5876-12-142