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Effective pulmonary delivery of an aerosolized plasmid DNA vaccine via surface acoustic wave nebulization
BACKGROUND: Pulmonary-delivered gene therapy promises to mitigate vaccine safety issues and reduce the need for needles and skilled personnel to use them. While plasmid DNA (pDNA) offers a rapid route to vaccine production without side effects or reliance on cold chain storage, its delivery to the l...
Autores principales: | Rajapaksa, Anushi E, Ho, Jenny J, Qi, Aisha, Bischof, Rob, Nguyen, Tri-Hung, Tate, Michelle, Piedrafita, David, McIntosh, Michelle P, Yeo, Leslie Y, Meeusen, Els, Coppel, Ross L, Friend, James R |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4040411/ https://www.ncbi.nlm.nih.gov/pubmed/24884387 http://dx.doi.org/10.1186/1465-9921-15-60 |
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