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Immunologic Basis for Long HCDR3s in Broadly Neutralizing Antibodies Against HIV-1

A large number of potent broadly neutralizing antibodies (bnAbs) against HIV-1 have been reported in recent years, raising hope for the possibility of an effective vaccine based on epitopes recognized by these protective antibodies. However, many of these bnAbs contain the long heavy chain complemen...

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Detalles Bibliográficos
Autores principales: Yu, Lei, Guan, Yongjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4040451/
https://www.ncbi.nlm.nih.gov/pubmed/24917864
http://dx.doi.org/10.3389/fimmu.2014.00250