Cytolethal distending toxin B as a cell-killing component of tumor-targeted anthrax toxin fusion proteins

Cytolethal distending toxin (Cdt) is produced by Gram-negative bacteria of several species. It is composed of three subunits, CdtA, CdtB, and CdtC, with CdtB being the catalytic subunit. We fused CdtB from Haemophilus ducreyi to the N-terminal 255 amino acids of Bacillus anthracis toxin lethal facto...

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Detalles Bibliográficos
Autores principales: Bachran, C, Hasikova, R, Leysath, C E, Sastalla, I, Zhang, Y, Fattah, R J, Liu, S, Leppla, S H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4040664/
https://www.ncbi.nlm.nih.gov/pubmed/24434511
http://dx.doi.org/10.1038/cddis.2013.540

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