OCT4 as a target of miR-34a stimulates p63 but inhibits p53 to promote human cell transformation

Human cell transformation is a key step for oncogenic development, which involves multiple pathways; however, the mechanism remains unclear. To test our hypothesis whether cell oncogenic transformation shares some mechanisms with the process of reprogramming non-stem cells to induced pluripotent ste...

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Detalles Bibliográficos
Autores principales: Ng, W L, Chen, G, Wang, M, Wang, H, Story, M, Shay, J W, Zhang, X, Wang, J, Amin, A R M R, Hu, B, Cucinotta, F A, Wang, Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4040665/
https://www.ncbi.nlm.nih.gov/pubmed/24457968
http://dx.doi.org/10.1038/cddis.2013.563

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