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A cell-penetrating peptide based on the interaction between c-Src and connexin43 reverses glioma stem cell phenotype
Connexin43 (Cx43), the main gap junction channel-forming protein in astrocytes, is downregulated in malignant gliomas. These tumors are composed of a heterogeneous population of cells that include many with stem-cell-like properties, called glioma stem cells (GSCs), which are highly tumorigenic and...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4040690/ https://www.ncbi.nlm.nih.gov/pubmed/24457967 http://dx.doi.org/10.1038/cddis.2013.560 |