Cargando…

A cell-penetrating peptide based on the interaction between c-Src and connexin43 reverses glioma stem cell phenotype

Connexin43 (Cx43), the main gap junction channel-forming protein in astrocytes, is downregulated in malignant gliomas. These tumors are composed of a heterogeneous population of cells that include many with stem-cell-like properties, called glioma stem cells (GSCs), which are highly tumorigenic and...

Descripción completa

Detalles Bibliográficos
Autores principales: Gangoso, E, Thirant, C, Chneiweiss, H, Medina, J M, Tabernero, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4040690/
https://www.ncbi.nlm.nih.gov/pubmed/24457967
http://dx.doi.org/10.1038/cddis.2013.560

Ejemplares similares